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KMID : 0604520150410030237
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Journal of the Society of Cosmetic Scientists of Korea
2015 Volume.41 No. 3 p.237 ~ p.241
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Anti-inflammatory Effect of Fallopia sachalinensis RonseDecr. Fruit
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Park Sung-Ha
Jeong Hyeon-Jeong
Park Byoung-Jun
Jeong Tae-Hwa
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Abstract
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To develop a new anti-inflammation agent for cosmetics, we investigated the anti-inflammatory activity of Fallopia sachalinensis RonseDecr. fruit extracts (FSR). FSR inhibited the pre-inflammatory cytokines (1L-1β, IL-6, TNF-α) and reduced NO production of RAW 264.7 macrophage cells in a dose-dependent manner and decreased the activity to about 51% at a concentration of 100 μg/mL. FSR suppressed not only the mRNA expression of iNOS and COX-2, but also the protein expression of iNOS and COX-2 in macrophage. The results suggested that FSR has considerable potential as a cosmetics ingredient with an anti-inflammatory effect.
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KEYWORD
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Fallopia sachalinensis RonseDecr., anti-inflammatory
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